Nagaland has recently received an official declaration as a Lumpy Skin Disease (LSD) positive state after the detection of the disease in four districts. Under The Prevention and Control of Infectious and Contagious Diseases in Animals Act, 2009, the Directorate of Animal Husbandry & Veterinary Services will implement necessary preventive measures in collaboration with the concerned state department. Lumpy skin disease, caused by the Capripox virus, poses significant morbidity risks to cattle, with potential economic losses due to reduced productivity, lower milk production, abortions, and damaged hides. As a notifiable disease recognized by the World Animal Health Organization (OIE), its rapid spread raises concerns over economic impacts, making it essential to curb its transmission. Apart from cattle and buffaloes, this disease also poses a threat to wildlife populations, including Deer, Bison, and Mithun. The disease is transmitted by flies, ticks, and mosquitoes, leading to symptoms like high fever, skin nodules, loss of appetite, nasal and eye discharges, and nodules formation on the body.